Cooling methods for neonates with hypoxia at risk of ischaemic brain damage - horizon scanning review

Record ID 32001000988
Authors' objectives:

To summarise the current research evidence on the effectiveness of cooling methods for neonates with hypoxia at risk of ischaemic brain damage.

Authors' recomendations: - Clinical impact: Although long-term follow-up data are not available, there is some indication that there may be health benefits for some babies who would otherwise be severely handicapped. There is, however, little information about potential harms, the timeframe for treatment or a comparison between the two available methods of cooling. - Service impact: Some training is required to use aEEG for selection of neonates and to apply the cooling methods. There will be some service impact with widespread diffusion because treatment may need to be given shortly after birth and a larger group of babies will need assessment of eligibility. - Patient issues: Perinatal asphyxia has serious consequences not only for individuals but also for their families. Treatments that may prevent brain damage are likely to be important for our society as a whole and there may be some pressure to use these technologies from parents with at risk babies. - Financial and overall NHS impact: Cooling of neonates to prevent continuing brain damage could represent a major health benefit with savings in terms of reduced costs of care. The patented cooling cap is likely to be more expensive than non-commercial whole body cooling. Research is needed to evaluate both cooling methods so that the more cost-effective technology is the one to diffuse.
Authors' methods: Overview
Project Status: Completed
Year Published: 2000
URL for published report:
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: England, United Kingdom
MeSH Terms
  • Hypoxia, Brain
  • Hypoxia-Ischemia, Brain
  • Infant, Newborn
Organisation Name: NIHR Horizon Scanning Centre
Contact Address: The NIHR Horizon Scanning Centre, Department of Public Health, Epidemiology, and Biostatistics, School of Health and Population Sciences, University of Birmingham, 90 Vincent Drive, Edgbaston, Birmingham, B15 2SP. United Kingdom. Tel: +44 121 414 7831, Fax: +44 121 2269
Contact Name:
Contact Email:
Copyright: National Horizon Scanning Centre
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.