Authors' recommendations: To estimate the accuracy of cervical cancer screening methods in Korea, we performed a meta-analysis among asymptomatic women for cervical cancer screening. The estimated sensitivity and specificity for pap smear were 0.84(95% CI:0.75-0.90) and 0.78 (95% CI:0.65-0.87) respectively, and the variability of diagnostic accuracy among studies using pap smear was relatively low compared with that of HPV testing. The cost-effectiveness analysis of the selected cervical cancer screening strategies was carried out with consideration of various screening intervals (1, 2, 3, or 5 year), starting ages (20 or 30 years), and discontinuation ages (lifetime, 79 years) for each screening method. The cost-effectiveness analysis of the selected cervical cancer screening strategies revealed that pap smear testing at 1-year intervals (aged 30 to life-time) was the most cost-effective strategy with an incremental cost-utility ratio (ICUR) below KRW 30,000,000won/QALY. For the estimation of representative diagnostic accuracy and economic evaluation of cervical screening methods, more studies are strongly warranted in various medical institutions targeting-asymptomatic women for cervical cancer screening.

Project Status: Completed

Year Published: 2014

URL for published report: http://www.neca.re.kr/center/researcher/report_view.jsp?boardNo=GA&seq=122&q=626f6172644e6f3d4741

English language abstract: An English language summary is available

Publication Type: Not Assigned

Country: South Korea

Organisation Name: National Evidence-based healthcare Collaborating Agency

Contact Address: National Evidence-based Healthcare Collaborating Agency (NECA), 3~5F Health and Welfare Social Administration B/D, 400 Neungdong-ro, Gwangjin-gu, Seoul, Korea.

Contact Name: int@neca.re.kr

Contact Email: int@neca.re.kr

Copyright: National Evidence-based Healthcare Collaborating Agency (NECA)