Is patient self-monitoring (including self-testing and self-management) of oral anticoagulation therapy safe, efficacious and cost-effective?
Thompson, L
Record ID 32014001082
English
Authors' recommendations:
• Meta-analyses of randomised controlled trials data in patients receiving long-term oral anticoagulation therapy with vitamin K antagonists report that self monitoring of INR reduces the rate of thromboembolic events, compared with usual care, without affecting the rate of major bleeding events or mortality.
• In subgroup analysis, self-management was more effective than self-testing.
• Analyses of outcomes by age and indication for therapy highlighted that there were reductions in thromboembolic events in those aged <55 years and in participants with a mechanical heart valve.
• Where quality of life is reported, the majority of studies record beneficial effects.
• Economic analyses suggest that in the UK healthcare setting, INR self monitoring is unlikely to be cost-effective when compared with usual care.
Details
Project Status:
Completed
Year Published:
2013
URL for published report:
http://www.healthcareimprovementscotland.org/our_work/technologies_and_medicines/shtg_-_evidence_notes/evidence_note_50.aspx
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
Scotland, United Kingdom
MeSH Terms
- Self Care
- Drug Monitoring
- Administration, Oral
Contact
Organisation Name:
Scottish Health Technologies Group
Contact Address:
Scottish Health Technologies Group, Delta House, 50 West Nile Street, Glasgow, G1 2NP Tel: 0141 225 6998
Contact Name:
his.shtg@nhs.scot
Contact Email:
his.shtg@nhs.scot
Copyright:
Healthcare Improvement Scotland
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.