Effectiveness of screening for endemic antibiotic resistant organisms (AROs) in hospital settings
Bond K, Tjosvold L, Harstall C
Record ID 32014001072
English
Authors' objectives:
The following research questions were addressed in this review:
1. What are the clinical effects of a universal screening strategy for ARO carriage when compared with no screening?
2. What are the clinical effects of a universal screening strategy for ARO carriage when compared with targeted screening (screening of selected patient populations)?
3. What are the clinical effects of targeted screening for ICU patients, surgical patients, and other high-risk patients (for example, patients on hemodialysis, transferred patients) compared with no screening?
Authors' recommendations:
ARO infections can have a serious impact on patients and hospital staffing resources and the cost and resources required for effective prevention and control of endemic AROs. Despite much research having been conducted on HA ARO infection prevention and control, there is currently little high-quality evidence that screening of patients (whether universal or targeted, and primarily relating to MRSA) is associated with reduction in HA ARO incidence, infection, mortality or morbidity in endemic settings. Results from a single, large RCT suggest that universal approaches to infection control may be more effective than approaches that aim to target single pathogens. Current clinical practice guidelines recommend that admission screening of high-risk patients be conducted for MRSA, VRE, and CROs. No guidelines currently recommend screening for ESBL-producing organisms. Given the current lack of reliable research evidence with which to guide decisions regarding screening, future research should focus on conducting well-designed, prospective studies that can disentangle the relative contributions of the measures used in the various approaches to HA ARO infection prevention and control.
Details
Project Status:
Completed
Year Published:
2014
URL for published report:
http://www.ihe.ca/advanced-search/effectiveness-of-screening-for-endemic-antibiotic-resistant-organisms-aros-in-hospital-settings
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
Canada
MeSH Terms
- Humans
- Hospitals
- Bacteria
- Anti-Bacterial Agents
- Diagnostic Tests, Routine
- Drug Resistance, Microbial
Contact
Organisation Name:
Institute of Health Economics
Contact Address:
1200, 10405 – Jasper Avenue, Edmonton, AB T5J 3N4, Canada. Tel: +1 780 448 4881 Fax: +1 780 448 0018
Contact Name:
info@ihe.ca
Contact Email:
info@ihe.ca
Copyright:
Institute of Health Economics (IHE)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.