Rosuvastatin: do we need another statin?
Record ID 32001000961
To summarise the available evidence on the use of rosuvastatin for the treatment and prevention of lipid disorders.
Authors' recomendations: - Rosuvastatin (Crestor(TM)) is a new synthetic agent for the treatment and prevention of lipid disorders, a risk factor for coronary heart disease. - Rosuvastatin is undergoing phase III clinical trials. A New Drug Application was submitted to the U.S. Food and Drug Administration in June, 2001. No information on the regulatory status in Canada is currently available. - Limited evidence from small clinical trials suggests that rosuvastatin may produce larger dose-dependent decreases in total cholesterol levels and low-density lipoprotein-cholesterol levels in hypercholesterolemic patients compared to other statins. There is insufficient evidence to draw conclusions about the safety of rosuvastatin. - The impact of rosuvastatin therapy on cardiac morbidity and mortality is not known. More experience is required to determine the effectiveness and relative benefits of this new drug.
Authors' methods: Overview
Project Status: Completed
URL for project: https://www.ccohta.ca/research/index.html
Year Published: 2001
English language abstract: An English language summary is available
Publication Type: Not Assigned
- Anticholesteremic Agents
- Coronary Disease
Organisation Name: Canadian Coordinating Office for Health Technology Assessment
Contact Address: 600-865 Carling Avenue, Ottawa, ON K1S 5S8 Canada. Tel: +1 613 226 2553, Fax: +1 613 226 5392;
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Copyright: Canadian Coordinating Office for Health Technology Assessment
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