Exparel (Bupivacaine liposome injectable suspension; Pacira Pharmaceuticals Inc.) for treatment of postoperative pain

Record ID 32014000974
English
Authors' objectives: Many patients (more than 80%) have postoperative pain or acute pain after surgery with fewer than 50% receiving adequate relief. Poorly controlled postoperative pain may negatively impact clinical outcomes and is associated with problems such as poor wound healing, deep vein thrombosis, pulmonary embolism, coronary ischemia, myocardial infarction, and pneumonia. Complications arising from ineffective postoperative pain management can reduce quality of life, lengthen hospital stays, increase readmission rates, and lead to development of chronic pain. Postoperative pain management may include intravenous medication delivered via a patient-controlled analgesia pump, epidural analgesia, spinal anesthesia, nerve blocks, local anesthetics, opioid and nonopioid analgesics, and nonsteroidal anti-inflammatory drugs. Bolus injection of local anesthetics into the surgical site is an option for pain control; however, the duration of effect is limited to several hours. A long-acting local anesthetic has the potential to improve postsurgical pain control, reduce the need for systemic opioid use, and reduce complications.
Details
Project Status: Completed
Year Published: 2014
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: United States
MeSH Terms
  • Pain, Postoperative
  • Injections, Epidural
Contact
Organisation Name: HAYES, Inc.
Contact Address: 157 S. Broad Street, Suite 200, Lansdale, PA 19446, USA. Tel: 215 855 0615; Fax: 215 855 5218
Contact Name: saleinfo@hayesinc.com
Contact Email: saleinfo@hayesinc.com
Copyright: 2014 Winifred S. Hayes, Inc
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