Management of acute exacerbations of chronic obstructive pulmonary disease
Agency for Healthcare Research and Quality (AHRQ)
Record ID 32001000947
The objectives of this report are to assess the evidence currently available on the diagnosis, prognosis, and management of acute exacerbation of chronic obstructive pulmonary disease (COPD), and on the use of noninvasive positive pressure ventilation (NPPV) in patients with acute respiratory failure secondary to acute exacerbation of COPD.
Authors' recomendations: Although many factors are associated with poor outcomes in patients with acute exacerbation of COPD, it is not possible to formulate accurate, clinically useful predictions concerning patients' prognoses. Hence, ongoing clinical monitoring is necessary for many patients. Several conservative therapies utilised for the management of acute exacerbation show benefit (antibiotics, corticosteroids, and bronchodilators); however, some therapies lack evidence of efficacy (mucolytics and physical therapy). The more aggressive strategy of NPPV benefits some patients with acute exacerbation of chronic obstructive pulmonary disease and acute respiratory failure.
Authors' methods: Systematic review
Project Status: Completed
URL for project: http://www.ahrq.gov/clinic/copdsum.htm
Year Published: 2001
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: United States
- Adrenal Cortex Hormones
- Anti-Bacterial Agents
- Bronchodilator Agents
- Lung Diseases, Obstructive
- Positive-Pressure Respiration
Organisation Name: Agency for Healthcare Research and Quality
Contact Address: Center for Outcomes and Evidence Technology Assessment Program, 540 Gaither Road, Rockville, MD 20850, USA. Tel: +1 301 427 1610; Fax: +1 301 427 1639;
Contact Name: firstname.lastname@example.org
Contact Email: email@example.com
Copyright: Agency for Healthcare Research and Quality (AHRQ)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.