Non-invasive prenatal testing: a review of the cost effectiveness and guidelines

CADTH
Record ID 32014000820
English
Authors' recommendations: When current prenatal testing programs were compared with alternate programs incorporating NIPT, program costs were increased in three studies and decreased in one study. Considering these discrepancies, results need to be interpreted with caution. At the present time, universal screening with NIPT appears to increase costs substantially and is unlikely to be feasible. However, use of NIPT in contingent screening, where only a certain proportion of pregnant women determined by the degree of risk receive NIPT, may be feasible. One guideline recommended the use of NIPT as an option for women at high risk in lieu of amniocentesis, and in case of a positive NIPT result, that no decision should be made without confirmatory invasive diagnostic testing.
Details
Project Status: Completed
Year Published: 2014
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Canada
MeSH Terms
  • Humans
  • Prenatal Diagnosis
Contact
Organisation Name: Canadian Agency for Drugs and Technologies in Health
Contact Address: 600-865 Carling Avenue, Ottawa, ON K1S 5S8 Canada. Tel: +1 613 226 2553; Fax: +1 613 226 5392;
Contact Name: requests@cadth.ca
Contact Email: requests@cadth.ca
Copyright: Canadian Agency for Drugs and Technologies in Health (CADTH)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.