[Effectiveness of treatments for carcinomas of an unknown primary site]
Hahn S, Lee J, Park NH, Kim J, Kang SN, Sohn HJ
Record ID 32014000415
Korean
Original Title:
원발부위불명 전이암 치료법의 유효성
Authors' recommendations:
Through the results of this study that was conducted with exploration based on small group analysis, clear superiority or inferiority between certain treatments could not be confirmed. However, through the work to organize evidence that had been accumulated through previous studies and to evaluate and integrate the evidence, the general orientation of treatment effects of different treatment methods could be identified and presented.
Among the primary anticancer chemotherapies in diverse combinations tried on patients with cancer of unknown primary sites, clear extensions of the survival periods and improvement in survival rates were observed in the case of complex anticancer chemotherapy including taxane. Survival outcomes when taxane and platinum were used in combination were better than when taxane combination treatment that did not include platinum or platinum combination treatment that did not include taxane was used, and it was much better than when other combination treatments that did not include taxane or platinum were used, supporting the hypothesis that the optimal combination is a combination of taxane and platinum.
These results can be utilized as basic grounds for selecting primary complex anticancer chemotherapies for patients with cancer of unknown primary sites and they also can be used as basic information necessary for creating base data through additional clinical studies.
Details
Project Status:
Completed
Year Published:
2010
URL for published report:
https://www.neca.re.kr/lay1/program/S1T11C145/report/view.do?seq=24
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
South Korea
MeSH Terms
- Neoplasm Metastasis
Contact
Organisation Name:
National Evidence-based healthcare Collaborating Agency
Contact Address:
National Evidence-based Healthcare Collaborating Agency (NECA), 3~5F Health and Welfare Social Administration B/D, 400 Neungdong-ro, Gwangjin-gu, Seoul, Korea.
Contact Name:
int@neca.re.kr
Contact Email:
int@neca.re.kr
Copyright:
National Evidence-based Healthcare Collaborating Agency (NECA)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.