[Image-guided radiosurgery and radiotherapy for central nervous systems tumors]

Pichon Riviere A, Augustovski F, Garcia Marti S, Glujovsky D, Alcaraz A, Lopez A, Bardach A, Ciapponi A, Spira C
Record ID 32014000298
Authors' objectives: To assess the available evidence on the efficacy, safety and coverage related aspects of radiosurgery and image-guided stereotactic radiotherapy in patients with central nervous system tumors.
Authors' recommendations: In those patients with brain MTS, two studies of adequate methodological quality suggest that fractioned stereotactic radiotherapy is a good treatment alternative, specially in terms of overall survival, for patients with 1-3 brain MTS, good performance status, and controlled systemic disease when surgery is not plausible. Both the clinical practice guidelines as well as the coverage policies support its use for this condition. For the primary CNS tumors assessed in this document, studies of poor methodological quality suggest that SRS and SRT are the only efficacious alternative when surgery is not possible or as adjuvant therapy, although further studies of good methodological design are required to accurately assess SRS/SRT efficacy in these conditions.
Project Status: Completed
Year Published: 2012
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Argentina
MeSH Terms
  • Humans
  • Central Nervous System Neoplasms
  • Radiotherapy, Image-Guided
  • Radiosurgery
Organisation Name: Institute for Clinical Effectiveness and Health Policy
Contact Address: Dr. Emilio Ravignani 2024, Buenos Aires - Argentina, C1414 CABA
Contact Name: info@iecs.org.ar
Contact Email: info@iecs.org.ar
Copyright: Institute for Clinical Effectiveness and Health Policy (IECS)
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