[Cryopreservation of parathyroid glands for deferred autologous transplant in the management of hyperparathyroidism with surgical indication]

Pichon Riviere A, Augustovski F, Garcia Marti S, Glujovsky D, Alcaraz A, Lopez A, Bardach A, Ciapponi A, Spira C
Record ID 32014000283
Authors' objectives: To assess the evidence available on the efficacy, safety and coverage policy related aspects on the use of cryopreservation of parathyroid glands in patients with hyperparathyroidism undergoing surgery.
Authors' recommendations: There is low methodological quality evidence suggesting that, in view of the low rate of success, cryopreservation of parathyroid glands for deferred autologous transplant would be a practice to be considered only at highly experienced centers. In addition, the cryopreservation period seems to significantly affect tissue function and effectiveness, therefore the deferral period should not be longer than strictly necessary. No clinical practice guidelines were found supporting the use of this technique as a therapeutic alternative for patients with hyperparathyroidism and surgical indication.
Project Status: Completed
Year Published: 2012
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Argentina
MeSH Terms
  • Cryopreservation
  • Hyperparathyroidism
  • Autografts
  • Parathyroid Glands
Organisation Name: Institute for Clinical Effectiveness and Health Policy
Contact Address: Dr. Emilio Ravignani 2024, Buenos Aires - Argentina, C1414 CABA
Contact Name: info@iecs.org.ar
Contact Email: info@iecs.org.ar
Copyright: Institute for Clinical Effectiveness and Health Policy (IECS)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.