[Use of antibiotic-loaded bone cement in primary hip and knee arthroplasty]
Pichon Riviere A, Augustovski F, Garcia Marti S, Alcaraz A, Glujovsky D, Lopez A, Rey-Ares L, Bardach A, Ciapponi A, Urtasun M
Record ID 32014000248
Spanish
Authors' objectives:
The purpose of this report is to assess the evidence available on the efficacy, safety and coverage policy related issues on the use of antibiotic-loaded bone cement in primary hip and knee arthroplasty.
Authors' recommendations:
The evidence found for primary THA was of moderate quality and it showed that ATB-loaded cement might add some clinical benefit to systemic prophylaxis, although there are no RCTs of adequate quality supporting this indication. The evidence found for TKAs was of good quality although contradictory regarding results. Some studies showed the benefits of adding ATB-loaded cement to the systemic antibiotic prophylaxis, however the most recent RCT, with the largest number of patients enrolled, found no clinical benefits associated to the use of antibiotic-loaded cement. In spite of the fact that evidence is not conclusive for THA and TKA, the clinical practice guidelines usually support its use, although in some cases they restrict it to patients considered at high risk.
Details
Project Status:
Completed
Year Published:
2013
URL for published report:
https://www.iecs.org.ar/home-ets/?cod_publicacion=1560&familia=5&origen_publicacion=buscador
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
Argentina
MeSH Terms
- Bone Cements
- Joint Prosthesis
- Arthroplasty, Replacement, Knee
- Arthroplasty, Replacement, Hip
Contact
Organisation Name:
Institute for Clinical Effectiveness and Health Policy
Contact Address:
Dr. Emilio Ravignani 2024, Buenos Aires - Argentina, C1414 CABA
Contact Name:
info@iecs.org.ar
Contact Email:
info@iecs.org.ar
Copyright:
Institute for Clinical Effectiveness and Health Policy (IECS)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.