[Detection of sperm DNA fragmentation (TUNEL, SCSA, SCD, COMET) and use of annexin columns (MACS) in assisted reproduction treatments]
Pichon Riviere A, Augustovski F, Garcia Marti S, Alcaraz A, Glujovsky D, Lopez A, Rey-Ares L, Bardach A, Ciapponi A, Mengarelli C
Record ID 32014000240
Spanish
Authors' objectives:
To assess the available evidence on the efficacy, safety and coverage policy related aspect on the use of sperm DNA fragmentation and the use of annexin columns in assisted reproduction treatments.
Authors' recommendations:
The quality of the evidence found for sperm DNA fragmentation assessment is poor. Observational studies show that the alterations diagnosed with Tunel and SCSA are associated with higher rates of miscarriages, however, so far, there have not been interventions which, based on this information, may allow improving the assisted reproductive treatment outcomes. That is why, the GPCs and health sponsors do not recommend sperm DNA fragmentation assays routinely. As regards, the annexin columns, there is no evidence on the benefit of its use in assisted reproduction.
Details
Project Status:
Completed
Year Published:
2013
URL for published report:
https://www.iecs.org.ar/home-ets/?cod_publicacion=1772&familia=5&origen_publicacion=buscador
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
Argentina
MeSH Terms
- Humans
- Semen Analysis
- DNA Fragmentation
- Reproductive Techniques, Assisted
Contact
Organisation Name:
Institute for Clinical Effectiveness and Health Policy
Contact Address:
Dr. Emilio Ravignani 2024, Buenos Aires - Argentina, C1414 CABA
Contact Name:
info@iecs.org.ar
Contact Email:
info@iecs.org.ar
Copyright:
Institute for Clinical Effectiveness and Health Policy (IECS)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.