JC virus antibody testing for patients with MS: a review of the diagnostic accuracy and guidelines

CADTH
Record ID 32014000197
English
Authors' recommendations: Anti-JCV antibody assays were able to identify anti-JCV antibodies in approximately 50-60% of natalizumab-treated MS patients or MS patients considering treatment with natalizumab. The StratifyJCV test was found to have a low false negative rate when urinary JCV-DNA was used as a positive reference. No evidence-based guidelines and testing algorithms for JCV antibodies in patients with MS were identified.
Details
Project Status: Completed
Year Published: 2013
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Canada
MeSH Terms
  • Humans
  • JC Virus
  • Multiple Sclerosis
  • Enzyme-Linked Immunosorbent Assay
  • Leukoencephalopathy, Progressive Multifocal
Contact
Organisation Name: Canadian Agency for Drugs and Technologies in Health
Contact Address: 600-865 Carling Avenue, Ottawa, ON K1S 5S8 Canada. Tel: +1 613 226 2553; Fax: +1 613 226 5392;
Contact Name: requests@cadth.ca
Contact Email: requests@cadth.ca
Copyright: Canadian Agency for Drugs and Technologies in Health (CADTH)
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