Non-steroidal anti-inflammatory drugs for pain: a review of safety
CADTH
Record ID 32014000098
English
Authors' recommendations:
In pain management, celecoxib and non-selective NSAIDs seem to have a similar overall risk of major cardiovascular adverse events even though cardiovascular risk was reportedly statistically significantly higher in celecoxib compared with naproxen. Statistically significantly fewer gastrointestinal adverse events were reported with the use of celecoxib compared with non-selective NSAIDs in the short term. Different non-selective NSAIDs appear to be associated with similar risks of serious gastrointestinal events. All non-selective NSAIDs except for naproxen were associated with similar risks of serious cardiovascular events.
Details
Project Status:
Completed
Year Published:
2013
URL for published report:
http://www.cadth.ca/media/pdf/htis/aug-2013/RC0471%20NSAID%20safety%20final.pdf
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
Canada
MeSH Terms
- Chronic Disease
- Pain
Contact
Organisation Name:
Canadian Agency for Drugs and Technologies in Health
Contact Address:
600-865 Carling Avenue, Ottawa, ON K1S 5S8 Canada. Tel: +1 613 226 2553; Fax: +1 613 226 5392;
Contact Name:
requests@cadth.ca
Contact Email:
requests@cadth.ca
Copyright:
Canadian Agency for Drugs and Technologies in Health (CADTH)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.