[A review of indications for ventricular assist device therapy]
Molina-Linde JM, Carlos-Gil AM, Baños-Álvarez E, Isabel-Gómez R, Beltrán-Calvo C
Record ID 32013001035
Authors' objectives: The goal of this review was to identify the indications for ventricular assist devices.
Authors' recomendations: Ventricular assist devices can be used as bridge to transplantation, bridge to ventricular recovery or destination therapy. The main indication for the implantation of a VAD as bridge to transplantation (for temporary or short-term use) is when the patient has a compromised hemodynamic status or a ventricular injury refractory to drug therapy. Destination therapy (for long-term or short-term use) can be considered for patients that are not candidate for transplantation, with ejection fraction of the left ventricle ≤ 25%, NYHA class IIIB/IV and peak oxygen consumption VO2<14mL/kg/min despite optimal inotropic therapy. Therapy as bridge to ventricular recovery was primarily indicated for patients with acute heart failure unresponsive to conventional treatment and with potentially reversible myocardial injury, as cardiogenic shock and acute myocarditis patients. In Spain, the two main indications for VAD implantation were its use as bridge to transplantation, and ventricular recovery. We recommend that further multicentric studies are performed by multidisciplinary teams using a adequate methodology (sample size, standardized final outcome measures, long-term follow-up, etc.) in order to improve and enhance the scientific evidence available in this field.
Project Status: Completed
Year Published: 2013
URL for published report: http://www.juntadeandalucia.es/salud/servicios/contenidos/nuevaaetsa/up/AETSA_2012%20_03_As_Ventricular.pdf
URL for additional information: http://www.juntadeandalucia.es/salud/servicios/contenidos/nuevaaetsa/up/AETSA_2012_03_As_Ventricular_eng.pdf
English language abstract: An English language summary is available
Publication Type: Not Assigned
- Heart-Assist Devices
- Heart Failure
Organisation Name: Andalusian Health Technology Assessment Area
Contact Address: Area de Evaluacion de Tecnologias Sanitarias Sanitarias de Andalucia (AETSA) Avda. Innovación, s/n Edificio Arena 1. Sevilla (Spain) Tel. +34 955 006 309
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Copyright: Andalusian Agency for Health Technology Assessment (AETSA)
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