Treatments for hyperemesis gravidarum and nausea and vomiting in pregnancy: a systematic review and economic assessment
O'Donnell A, McParlin C, Robson SC, Beyer F, Moloney E, Bryant A, Bradley J, Muirhead C, Nelson-Piercy C, Newbury-Birch D, Norman J, Simpson E, Swallow B, Yates L, Vale L
Record ID 32013001000
Authors' objectives: Nausea and vomiting in pregnancy (NVP) affects up to 85% of all women during pregnancy, but for the majority self-management suffices. For the remainder, symptoms are more severe and the most severe form of NVP – hyperemesis gravidarum (HG) – affects 0.3–1.0% of pregnant women. There is no widely accepted point at which NVP becomes HG. This study aimed to determine the relative clinical effectiveness and cost-effectiveness of treatments for NVP and HG.
Authors' recomendations: There was evidence of some improvement in symptoms for some treatments, but these data may not be transferable across disease severities. Methodologically sound and larger trials of the main therapies considered within the UK NHS are needed.
Project Status: Completed
URL for project: http://www.nets.nihr.ac.uk/projects/hta/1215201
Year Published: 2016
URL for published report: http://www.journalslibrary.nihr.ac.uk/hta/hta20740/#/abstract
English language abstract: An English language summary is available
Publication Type: Not Assigned
- Hyperemesis Gravidarum
Organisation Name: NIHR Health Technology Assessment programme
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