Faecal calprotectin testing for differentiating amongst inflammatory and non-inflammatory bowel diseases: a systematic review and economic evaluation
Waugh N, Cummins E, Royle P, Kandala NB, Shyangdan D, Arasaradnam R, Clar C, Johnston R
Record ID 32013000935
English
Authors' objectives:
To review the value of FC for distinguishing between IBD and non-IBD.
Authors' recommendations:
Faecal calprotectin can be a highly sensitive way of detecting IBD, although there are inevitably trade-offs between sensitivity and specificity, with some false positives (IBS with positive calprotectin) if a low calprotectin cut-off is used. In most cases, a negative calprotectin rules out IBD, thereby sparing most people with IBS from having to have invasive investigations, such as colonoscopy.
Details
Project Status:
Completed
Year Published:
2013
URL for published report:
http://www.journalslibrary.nihr.ac.uk/hta/volume-17/issue-55
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
England, United Kingdom
MeSH Terms
- Adult
- Child
- Diagnosis, Differential
- Middle Aged
- Quality-Adjusted Life Years
- Sensitivity and Specificity
- Colonoscopy
- Enzyme-Linked Immunosorbent Assay
- Feces
- Inflammatory Bowel Diseases
- Irritable Bowel Syndrome
- Leukocyte L1 Antigen Complex
Contact
Organisation Name:
NIHR Health Technology Assessment programme
Contact Address:
NIHR Journals Library, National Institute for Health and Care Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK
Contact Name:
journals.library@nihr.ac.uk
Contact Email:
journals.library@nihr.ac.uk
Copyright:
2013 Queen's Printer and Controller of HMSO
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.