[Duodeno-jejunal bypass liner (DJBL) for patients with obesity, with/without type 2 diabetes mellitus]

Fischer S, Zechmeister-Koss I, Huic M
Record ID 32013000924
Authors' objectives: This systematic review evaluates the efficacy and safety of the duodenal-jejunal bypass liner (DJBL) for the treatment of a) patients with obesity ≥ grade II with or ≥ grade III without comorbidities and b) patients with Type 2 diabetes mellitus + obesity ≥ grade I. The DJBL is a minimal-invasive method to reduce body weight and to control Type 2 diabetes mellitus (Type 2 DM). The device is a 60 cm long synthetic sleeve, which is endoscopically delivered into the duodenum and a small part of the jejunum.
Authors' recomendations: The analysed studies suggest a short-term reduction of body weight in obese patients. Overall, the available evidence is insufficient to assess the efficacy and safety of the intervention for the treatment of patients with obesity (+ comorbidities) or Type 2 diabetes mellitus + obesity. Currently, inclusion into the hospital benefit catalogue is not recommended. We propose re-evaluation in 2016 when results from studies that assess the commercialised version of the DJBL will be available.
Project Status: Completed
Year Published: 2013
URL for published report: http://eprints.hta.lbg.ac.at/1008
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Austria
MeSH Terms
  • Diabetes Mellitus, Type 2
  • Duodenum
  • Jejunum
  • Obesity
  • Weight Loss
Organisation Name: Ludwig Boltzmann Institute for Health Technology Assessment
Contact Address: Ludwig Boltzmann Institute for fuer Health Technology Assessment (LBI-HTA), Garnisongasse 7/rechte Stiege Mezzanin (Top 20), 1090 Vienna, Austria. Tel: +43 1 236 8119 - 0 Fax: +43 1 236 8119 - 99
Contact Name: tarquin.mittermayr@aihta.at
Contact Email: office@aihta.at
Copyright: Ludwig Boltzmann Institut fuer Health Technology Assessment (LBI-HTA)
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