[Percutaneous transluminal septal myocardial ablation (PTSMA) in hypertrophic obstructive cardiomyopathy (HOCM)]

Wild C
Record ID 32013000922
German
Authors' objectives: Hypertrophic cardiomyopathy (HCM) is a rare primary myocardial disease with a prevalence of 0.2%. HCM is hereditary and frequently appears in familial clusters. In a portion of the patients (approx. 70%) it results, under exertion, to an obstruction of the left ventricular outflow tract: hypertrophic-obstructive cardiomyopathy/HOCM. HOCM is associated with sudden cardiac death. In addition to conventional methods (medicines), interventional or operative methods are also applied in the treatment of symptomatic HOCM patients.
Authors' recommendations: The question whether PTMSA is equal or non-inferior to myectomy – in efficacy and safety – has been controversially discussed in forums for a long time. Three international professional societies have recommended myectomy as 1st line therapy. Since it concerns a very small, well-defined patient group and a volume increase is not to be expected, it is recommended that the intervention should only be carried out in highly-specialised centres with many years of experience in the interventional treatment of cardiomyopathies in Austria – upon the condition of participating in one of the already existing registries.
Details
Project Status: Completed
Year Published: 2013
URL for published report: http://eprints.hta.lbg.ac.at/1006
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Austria
MeSH Terms
  • Cardiomyopathy, Hypertrophic
  • Catheter Ablation
Contact
Organisation Name: Ludwig Boltzmann Institute for Health Technology Assessment
Contact Address: Ludwig Boltzmann Institute for fuer Health Technology Assessment (LBI-HTA), Garnisongasse 7/rechte Stiege Mezzanin (Top 20), 1090 Vienna, Austria. Tel: +43 1 236 8119 - 0 Fax: +43 1 236 8119 - 99
Contact Name: tarquin.mittermayr@aihta.at
Contact Email: office@aihta.at
Copyright: Ludwig Boltzmann Institut fuer Health Technology Assessment (LBI-HTA)
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