[Repair of cartilage defects via matrix-associated autologous chondrocyte immigration]

Wild C
Record ID 32013000918
German
Authors' objectives: Several mechanical methods, such as microfracture, debridement and/or lavage, mosaicplasty, but also the more complex method of tissue engineering - autologeous chondroyte implantation - are clinically applied for the treatment of chondral and osteochondral lesions of the knee. This report evaluates whether the implantation of a ready-made cell-free collagen-typ Imatrix (CaReS®-1S) leads to better results than these established methods.
Authors' recommendations: The inclusion of CaReS®-1S into the hospital benefit catalogue is not recommended. The currently available evidence is not sufficient to evaluate the efficacy and safety of the implantation of CaReS®-1 in comparison to standard interventions. We recommend a re-evaluation once controlled clinical studies have become available.
Details
Project Status: Completed
Year Published: 2013
URL for published report: http://eprints.hta.lbg.ac.at/1002/#
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Austria
MeSH Terms
  • Chondrocytes
  • Regeneration
  • Transplantation, Autologous
Contact
Organisation Name: Ludwig Boltzmann Institute for Health Technology Assessment
Contact Address: Ludwig Boltzmann Institute for fuer Health Technology Assessment (LBI-HTA), Garnisongasse 7/rechte Stiege Mezzanin (Top 20), 1090 Vienna, Austria. Tel: +43 1 236 8119 - 0 Fax: +43 1 236 8119 - 99
Contact Name: tarquin.mittermayr@aihta.at
Contact Email: office@aihta.at
Copyright: Ludwig Boltzmann Institut fuer Health Technology Assessment (LBI-HTA)
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