[Efficacy and cost-effectiveness of molecular techniques in the intraoperative assessment of the sentinel lymph node]
García Estepa R, Martínez Férez IM, Adam Blanco D, Márquez Peláez S, Rodríguez López R
Record ID 32013000747
Spanish
Authors' objectives:
To assess the efficacy and the cost-effectiveness of OSNA intraoperative test compared to conventional techniques (intraoperative and postoperative) in the detection of metastasis in the sentinel node in breast cancer patients.
Authors' recommendations:
The intraoperative OSNA assay presents a high agreement, sensitivity and specificity regard to the reference postoperative histopathological analysis.
The intraoperative OSNA assay presents greater sensitivity than the conventional intraoperative tests of imprint cytology and staining of frozen sections.
The OSNA clinical utility remains to be determined. Prospective studies would be required to determine their prognostic ability.
With the limited information about economic efficiency available and the estimations performed, the OSNA test could be considered an alternative to histopathological analysis that would save costs, but it has lower diagnostic ability.
Details
Project Status:
Completed
URL for project:
https://www.aetsa.org/publicacion/eficacia-y-coste-efectividad-de-las-tecnicas-moleculares-en-la-valoracion-intra-operatoria-del-ganglio-centinela/
Year Published:
2013
URL for published report:
https://www.aetsa.org/download/publicaciones/antiguas/AETSA_2010_3_GanglioCentinela_OSNA.pdf
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
Spain
MeSH Terms
- Humans
- Intraoperative Care
- Lymph Nodes
- Lymphatic Metastasis
- Neoplasm Staging
- Nucleic Acid Amplification Techniques
- Predictive Value of Tests
Contact
Organisation Name:
Andalusian Health Technology Assessment Area
Contact Address:
Area de Evaluacion de Tecnologias Sanitarias Sanitarias de Andalucia (AETSA) Avda. Innovación, s/n Edificio Arena 1. Sevilla (Spain) Tel. +34 955 006 309
Contact Name:
aetsa.csalud@juntadeandalucia.es
Contact Email:
aetsa.csalud@juntadeandalucia.es
Copyright:
Andalusian Agency for Health Technology Assessment (AETSA)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.