Migraine in children: preventive pharmacologic treatments
Shamliyan TA, Kane RL, Ramakrishnan R, Taylor FR
Record ID 32013000722
English
Authors' objectives:
To assess the comparative effectiveness and safety of preventive pharmacologic treatments for community-dwelling children with episodic or chronic migraine.
Authors' recommendations:
Limited low-strength evidence suggests that propranolol was more effective than placebo for preventing episodic migraine in children, with no bothersome adverse effects that could lead to treatment discontinuation. Long-term preventive benefits are unknown both for drugs and nonpharmacologic interventions. No studies examined quality of life or provided evidence for individualized treatment decisions. Future randomized trials of drugs with favorable benefits-to-harms ratio in adults are needed to identify effective and safe treatments to prevent episodic and chronic migraine in children.
Details
Project Status:
Completed
Year Published:
2013
URL for published report:
http://www.effectivehealthcare.ahrq.gov/ehc/products/313/1515/migraine-children-report-130524.pdf
URL for additional information:
http://www.effectivehealthcare.ahrq.gov/search-for-guides-reviews-and-reports/?pageaction=displayproduct&productid=1520
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
United States
MeSH Terms
- Migraine Disorders
Contact
Organisation Name:
Agency for Healthcare Research and Quality
Contact Address:
The Evidence-based Practice Center (EPC) Program, Center for Evidence and Practice Improvement, 5600 Fishers Lane, Rockville, MD 20857, USA. Tel: +1 301 427 1550
Contact Name:
The EPC Program
Contact Email:
epc@ahrq.hhs.gov
Copyright:
Agency for Healthcare Research and Quality (AHRQ)
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