Treatments for seasonal allergic rhinitis
Glacy J, Putnam K, Godfrey S, Falzon L, Mauger B, Samson D, Aronson N
Record ID 32013000718
Authors' objectives: This review compared the effectiveness and common adverse events of medication classes used to treat seasonal allergic rhinitis (SAR) in adolescents and adults, in pregnant women, and in children. We sought to compare the following classes of drugs: oral and nasal antihistamines and decongestants; intranasal corticosteroids, mast cell stabilizers (cromolyn), and anticholinergics (ipratropium); oral leukotriene receptor antagonists (montelukast); and nasal saline.
Authors' recommendations: Several effectiveness comparisons demonstrated similarity of treatments for selected outcomes. For most harms comparisons, the evidence was insufficient. Conclusions were limited by (1) lack of comparative evidence for all drugs within each class and (2) lack of evidence on the magnitude of symptom change that constitutes a minimal clinically important difference.
Project Status: Completed
Year Published: 2013
URL for published report: http://www.effectivehealthcare.ahrq.gov/ehc/products/376/1588/allergy-seasonal-report-130711.pdf
URL for additional information: http://www.effectivehealthcare.ahrq.gov/search-for-guides-reviews-and-reports/?pageaction=displayproduct&productid=1587
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: United States
- Rhinitis, Allergic, Seasonal
Organisation Name: Agency for Healthcare Research and Quality
Contact Address: Center for Outcomes and Evidence Technology Assessment Program, 540 Gaither Road, Rockville, MD 20850, USA. Tel: +1 301 427 1610; Fax: +1 301 427 1639;
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Copyright: Agency for Healthcare Research and Quality (AHRQ)
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