Wireless capsule endoscopy in the diagnosis of small bowel disease

Bernardini F, Cerbo M, Jefferson T, Lo Scalzo A, Ratti M
Record ID 32013000655
Authors' objectives: To identify and summarise available evidence about the diagnostic accuracy and safety of WCE for Obscure Gastrointestinal Bleeding, Crohn's disease, familiar polyposis, and Celiac disease in the small bowel, its related costs and acceptability.
Authors' recomendations: Based on evidence from one randomised controlled trial the WCE appears dominant for the diagnosis of Obscure Gastrointestinal Bleeding in the small bowel compared to Push Enteroscopy. However its dominance is based on tolerability, rather than proof of a superior diagnostic accuracy. The WCE procedure has a high failure rate, results in serious harms in 1% of cases, but is more acceptable to patients than its alternatives. Given its tiny evidence base, high cost, and potentially high failure rate, the WCE procedure should be only be reimbursed if used in a valid evidence-generating framework.
Project Status: Completed
Year Published: 2008
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Italy
MeSH Terms
  • Intestine, Small
  • Wireless Technology
Organisation Name: The Italian National Agency for Regional Health Services (Agenas)
Contact Address: Agenzia nazionale per i servizi sanitari regionali, Via Puglie 23, 00187 Rome, Italy
Contact Name: hta@agenas.it
Contact Email: hta@agenas.it
Copyright: Italian Ministry of Health and Agenas
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.