Renal artery ablation in patients with treatment-resistant hypertension: a systematic review

Corio M, Abraha I, Lopatriello S, Taddei S, Nocco U, Perrini MR, Filippi C, Vassanelli C, Jefferson T, Cerbo M
Record ID 32013000650
English
Authors' objectives: The aim of this systematic review is to identify and synthesize the available evidence about the effectiveness, safety and cost-effectiveness of denervation of renal artery by catheterbased radio-ablation in patients with resistant hypertension and to measure the potential economic impact of its use and diffusion in one Italian Regional Health System (Veneto Region).
Authors' recommendations: Clinical comparative studies included in this systematic review point out a significant reduction of blood pressure levels (both systolic and diastolic) in patients with treatment resistant essential hypertension. However since the available evidence is scarce, there is a need for more comparative clinical studies with longer follow-up. Long term efficacy and safety data are required to assess the actual effect of the renal artery ablation on the blood pressure and, accordingly, to evaluate how blood pressure reduction could affect the development of hypertension related diseases and mortality. An economic evaluation for renal artery ablation should be performed alongside such evidence generation studies.
Details
Project Status: Completed
Year Published: 2012
URL for published report: http://www.salute.gov.it/imgs/C_17_pagineAree_1202_listaFile_itemName_18_file.pdf
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Italy
MeSH Terms
  • Humans
  • Hypertension, Renal
  • Angioplasty, Balloon
  • Drug Resistance
Contact
Organisation Name: The Italian National Agency for Regional Health Services (Agenas)
Contact Address: Agenzia nazionale per i servizi sanitari regionali, Via Puglie 23, 00187 Rome, Italy
Contact Name: hta@agenas.it
Contact Email: hta@agenas.it
Copyright: Italian Ministry of Health and Agenas
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.