Polylactic-glycolic acid absorbable synthetic suture (Pgla) plus antibacterial: a systematic review

Perrini MR, Montedori A, Giani E, Rivoiro C, Corio M, Jefferson T, Cerbo M
Record ID 32013000649
English
Authors' objectives: The aim of this systematic review is to identify, appraise and synthesize the available evidence about the effectiveness, safety and economic data of sutures (PGLA) plus antibacterial compared to standard sutures (PGLA) without antibacterial.
Authors' recommendations: In the studies included, different outcomes and age groups and heterogeneous follow up time coupled with unclear reporting led to a considerable loss of data. Since the available evidence is scarce and heterogeneous there is a need of a large multicenter study to test the equipoise currently visible in the data presented in this review. Until such time clear evidence of dominance of Triclosan coated sutures is not available. Besides, given the higher cost of suture plus antibacterial compared to standard suture, economic studies should be performed to have clear and useful evidence for decision making.
Details
Project Status: Completed
Year Published: 2012
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Italy
MeSH Terms
  • Anti-Bacterial Agents
  • Antimicrobial Cationic Peptides
Contact
Organisation Name: The Italian National Agency for Regional Health Services (Agenas)
Contact Address: Agenzia nazionale per i servizi sanitari regionali, Via Puglie 23, 00187 Rome, Italy
Contact Name: hta@agenas.it
Contact Email: hta@agenas.it
Copyright: Italian Ministry of Health and Agenas
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.