[Fertility preservation in girls and young women in whom potentially gonadotoxic treatment is planned or has been performed]

Waern M, Eriksson M, Goldkuhl C, Jarfelt M, Lundin K, Milenkovic M, Strandell A, Svanberg T, Thurin-Kjellberg A, Sjögren P
Record ID 32013000619
Swedish
Authors' objectives: Does fertility preservation (oocyte vitrification, or transplantation of cryopreserved ovarian tissue) for girls and young women in whom potentially gonadotoxic treatment is planned or has been performed, improve their chances to give birth and improve their quality of life, compared to no fertility preservation, and how effective are the methods?
Authors' recomendations: Fertility preservation techniques by oocyte vitrification or freezing of ovarian tissue are under development. Live births are reported but the efficacy of the subsequent fertility treatment is yet unknown. In addition to the oncologist's counseling prior to gonadotoxic treatment, counseling by a fertility specialist, or fertility preservation may improve the quality of life. Very low quality of evidence. The risks associated with the procedures are generally low. The risk of premature ovarian failure varies widely, and reliable predictive models are lacking.
Details
Project Status: Completed
Year Published: 2013
English language abstract: An English language summary is available
Publication Type: Not Assigned
MeSH Terms
  • Female
  • Fertility Preservation
  • Immunosuppressive Agents
Contact
Organisation Name: The Regional Health Technology Assessment Centre
Contact Address: The Regional Health Technology Assessment Centre, Region Vastra Gotaland, HTA-centrum, Roda Straket 8, Sahlgrenska Universitetssjukhuset, 413 45 GOTHENBORG, Sweden
Contact Name: hta-centrum@vgregion.se
Contact Email: hta-centrum@vgregion.se
Copyright: The Regional Health Technology Assessment Centre (HTA-centrum), Region Vastra Gotaland
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