The clinical and cost effectiveness of long-term ventricular assist devices (VADs) as a bridge-to-transplant in adults
McIntosh H, Myles S
            Record ID 32013000462
            English
                                                            
                Authors' recommendations:
                Long-term ventricular assist devices can act as a bridge-to-transplant to allow heart transplant candidates who would otherwise become transplant-ineligible or die on the waiting list to survive to transplantation.
There are no published randomised controlled trials of ventricular assist devices as bridge-totransplant.
There is evidence from observational studies of improvement in functional status and quality of life during ventricular assist device support as bridge-to-transplant, and improved survival to transplant with second generation compared with first generation devices.
Implantation of contemporary ventricular assist devices remains associated with serious adverse events.
Ventricular assist device support as bridge to- transplant is not cost effective at currently accepted thresholds in the United Kingdom.
            
                                    
            Details
                        
                Project Status:
                Completed
            
                                                            
                Year Published:
                2011
            
                                    
                URL for published report:
                http://www.healthcareimprovementscotland.org/our_work/technologies_and_medicines/earlier_evidence_notes/evidence_note_39.aspx
            
                                                            
                English language abstract:
                An English language summary is available
            
                                    
                Publication Type:
                Not Assigned
            
                                    
                Country:
                Scotland, United Kingdom
            
                                                
                        MeSH Terms
            - Humans
 - Heart-Assist Devices
 - Cost-Benefit Analysis
 - Heart Transplantation
 - Heart Failure
 
Contact
                        
                Organisation Name:
                Scottish Health Technologies Group
            
            
                        
                Contact Address:
                Scottish Health Technologies Group, Delta House, 50 West Nile Street, Glasgow, G1 2NP  Tel: 0141 225 6998
            
                                    
                Contact Name:
                his.shtg@nhs.scot
            
                                    
                Contact Email:
                his.shtg@nhs.scot
            
                                    
                Copyright:
                Healthcare Improvement Scotland
            
                    
                This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.