The clinical and cost effectiveness of long-term ventricular assist devices (VADs) as a bridge-to-transplant in adults

McIntosh H, Myles S
Record ID 32013000462
Authors' recommendations: Long-term ventricular assist devices can act as a bridge-to-transplant to allow heart transplant candidates who would otherwise become transplant-ineligible or die on the waiting list to survive to transplantation. There are no published randomised controlled trials of ventricular assist devices as bridge-totransplant. There is evidence from observational studies of improvement in functional status and quality of life during ventricular assist device support as bridge-to-transplant, and improved survival to transplant with second generation compared with first generation devices. Implantation of contemporary ventricular assist devices remains associated with serious adverse events. Ventricular assist device support as bridge to- transplant is not cost effective at currently accepted thresholds in the United Kingdom.
Project Status: Completed
Year Published: 2011
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Scotland, United Kingdom
MeSH Terms
  • Humans
  • Heart-Assist Devices
  • Cost-Benefit Analysis
  • Heart Transplantation
  • Heart Failure
Organisation Name: Scottish Health Technologies Group
Contact Address: Scottish Health Technologies Group, Delta House, 50 West Nile Street, Glasgow, G1 2NP Tel: 0141 225 6998
Contact Name:
Contact Email:
Copyright: Healthcare Improvement Scotland
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