Noninvasive positive-pressure ventilation (NPPV) for acute respiratory failure

Williams JW, Jr., Cox CE, Hargett CW, Gilstrap DL, Castillo CE, Govert JA, Lugogo NL, Coeytaux RR, McCrory DC, Hasselblad V, McBroom AJ, Posey R, Gray R, Sanders GD
Record ID 32013000199
English
Authors' objectives: Noninvasive positive-pressure ventilation (NPPV) is a form of mechanical ventilatory support delivered to patients with acute respiratory failure through a noninvasive interface. In patients with a range of etiologies for acute respiratory failure, NPPV has the potential to reduce complications and improve outcomes compared to invasive ventilation.
Authors' recommendations: For patients with acute respiratory failure due to severe exacerbations of COPD or congestive heart failure, NPPV improves outcomes compared to supportive care alone. Current evidence suggests potential benefit for patients with acute respiratory failure who are postoperative or post-transplant, and in selected populations, as a method to facilitate weaning from invasive ventilation or prevent recurrent respiratory failure postextubation. Limited evidence shows similar treatment effects across different settings and the possibility of less benefit in trials designed to replicate usual clinical practice.
Details
Project Status: Completed
Year Published: 2012
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: United States
MeSH Terms
  • Positive-Pressure Respiration
  • Acute Disease
Contact
Organisation Name: Agency for Healthcare Research and Quality
Contact Address: Center for Outcomes and Evidence Technology Assessment Program, 540 Gaither Road, Rockville, MD 20850, USA. Tel: +1 301 427 1610; Fax: +1 301 427 1639;
Contact Name: martin.erlichman@ahrq.hhs.gov
Contact Email: martin.erlichman@ahrq.hhs.gov
Copyright: Agency for Healthcare Research and Quality (AHRQ)
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