Vitamin D supplementation in patients with active or latent tuberculosis

Lönnermark E, Dotevall L, Fjällbrant H, Kötz K, Sjövall H , Sundell N, Svanberg T, Trollfors B, Wikberg Adania U, Sjögren P
Record ID 32013000122
English
Authors' objectives: Does vitamin D supplementation, as compared to no treatment or placebo, reduce mortality, slow progression of disease, reduce disease susceptibility or increase the quality of life in patients with active or latent TB infection?
Authors' recommendations: Vitamin D supplementation has no significant effect on mortality (low quality of evidence), or disease progression in patients with active TB (very low quality of evidence). No articles were identified studying the effect of vitamin D supplementation on quality of life in patients with active TB. Neither was any studies identified with these outcomes in patients with latent TB. In patients with very low vitamin D levels (25OHD levels below 30-50 nmol/L), treatment is probably indicated irrespective of TB status but this aspect was not analysed in the current HTA report.
Details
Project Status: Completed
Year Published: 2012
URL for published report: http://www.sahlgrenska.se/upload/SU/HTA-centrum/HTA-rapporter/HTA-report%20Vitamin%20D%20supplementation%20in%20patients%20with%20active%20or%20latent%20tuberculosis%20%20till%20pubiceringl.%20pdf.pdf
URL for additional information: http://www.sahlgrenska.se/sv/SU/Forskning/HTA-centrum/Hogerkolumn-undersidor/Publicerade-rapporter/
English language abstract: An English language summary is available
Publication Type: Not Assigned
MeSH Terms
  • Tuberculosis
  • Vitamin D
  • Vitamins
  • Mycobacterium tuberculosis
Contact
Organisation Name: The Regional Health Technology Assessment Centre
Contact Address: The Regional Health Technology Assessment Centre, Region Vastra Gotaland, HTA-centrum, Roda Straket 8, Sahlgrenska Universitetssjukhuset, 413 45 GOTHENBORG, Sweden
Contact Name: hta-centrum@vgregion.se
Contact Email: hta-centrum@vgregion.se
Copyright: The Regional Health Technology Assessment Centre (HTA-centrum), Region Vastra Gotaland
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.