[Radiofrequency ablation of primary tumors of the gastrointestinal tract (colorectal and pancreatic cancer)]

Warmuth M, Adlbrecht C
Record ID 32012000776
German
Authors' objectives: Radiofrequency ablation (RFA) is a relatively new, percutaneous minimallyinvasive, endoscopic or intraoperative ablation method which destroys tumors by local application of heat. This systematic review evaluates two indications of RFA for the treatment of gastrointestinal primary tumors: colorectal cancer and pancreatic cancer. Dependent on the tumor stage, surgery and/or chemotherapy and/or radiotherapy represent the gold-standard of treatment. However, in advanced disease stages and patients with severe comorbidities, these interventions may not be feasible. In these cases, RFA may represent an alternative or complementary treatment option.
Authors' recommendations: According to GRADE, the quality of evidence is very low due to the uncontrolled study design of the included case-series. Overall, the available evidence is insufficient to assess the efficacy and safety of RFA for the treatment of pancreatic cancer. Furthermore, there is no evidence concerning RFA for the treatment of colorectal cancer. Currently, the inclusion into the hospital benefit catalogue is not recommended.
Details
Project Status: Completed
Year Published: 2012
URL for published report: http://eprints.hta.lbg.ac.at/962/1/DSD_58.pdf
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Austria
MeSH Terms
  • Colorectal Neoplasms
  • Tomography, X-Ray Computed
  • Pancreatic Neoplasms
Contact
Organisation Name: Ludwig Boltzmann Institute for Health Technology Assessment
Contact Address: Ludwig Boltzmann Institute for fuer Health Technology Assessment (LBI-HTA), Garnisongasse 7/rechte Stiege Mezzanin (Top 20), 1090 Vienna, Austria. Tel: +43 1 236 8119 - 0 Fax: +43 1 236 8119 - 99
Contact Name: tarquin.mittermayr@aihta.at
Contact Email: office@aihta.at
Copyright: Ludwig Boltzmann Institut fuer Health Technology Assessment (LBI-HTA)
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