Combination therapy (interferon alfa and ribavirin) in the treatment of chronic hepatitis C: a rapid and systematic review
Shepherd J, Waugh N, Hewitson P
Record ID 32001000002
English
Authors' objectives:
To review the clinical effectiveness and cost-effectiveness of combination therapy with interferon alfa and ribavirin in patients with chronic hepatitis C.
Authors' recommendations:
There is benefit associated with combination therapy and treatment can be cost-effective. It is appropriate to offer 6 months of combination therapy as first-line treatment to patients not previously treated with interferon and also to patients who have relapsed following a previous course of interferon. At 6 months, continuation of treatment should depend on factors that may predict a good sustained response.
Authors' methods:
Systematic review
Details
Project Status:
Completed
URL for project:
http://www.hta.ac.uk/1178
Year Published:
2000
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
England, United Kingdom
MeSH Terms
- Costs and Cost Analysis
- Drug Therapy, Combination
- Hepatitis C, Chronic
- Interferon-alpha
- Ribavirin
Contact
Organisation Name:
NIHR Health Technology Assessment programme
Contact Address:
NIHR Journals Library, National Institute for Health and Care Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK
Contact Name:
journals.library@nihr.ac.uk
Contact Email:
journals.library@nihr.ac.uk
Copyright:
2009 Queen's Printer and Controller of HMSO
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.