Authors' recommendations: Hepatic (liver) disease is a broad term that refers to any general disruption of normal liver function resulting in illness. Liver disease may be the result of alcohol abuse, cirrhosis, drug-induced liver disease, infectious hepatitis, hemachromatosis, and malignancies, such as hepatocellular carcinoma (HCC) and cholangiocarcinoma. HCC ranks as the fifth most common malignancy in the world, resulting in an estimated 500,000 deaths each year. Hepatic resection is a treatment option for some types of hepatic disease, including HCC and metastatic liver tumors. Hepatic resection has typically been associated with significant mortality and morbidity due to the risk of intraoperative blood loss and risk of postoperative liver failure. The most commonly used procedure to stop bleeding and control blood loss during hepatic resection is the Pringle maneuver or hilar clamping. However, hilar clamping may decrease cardiac output and increase systemic vascular resistance during surgery. Furthermore, it may cause ischemic damage to the remaining portions of the liver, causing complications, particularly in patients with cirrhosis. Recently, new electrosurgical dissecting and coagulating instruments have been developed to minimize blood loss during hepatic resection and reduce rates of transfusion.

Project Status: Completed

Year Published: 2012

URL for published report: The report may be purchased from:http://www.hayesinc.com/hayes/crd/?crd=13853

English language abstract: An English language summary is available

Publication Type: Not Assigned

Country: United States

Organisation Name: HAYES, Inc.

Contact Address: 157 S. Broad Street, Suite 200, Lansdale, PA 19446, USA. Tel: 215 855 0615; Fax: 215 855 5218

Contact Name: saleinfo@hayesinc.com

Contact Email: saleinfo@hayesinc.com

Copyright: 2012 Winifred S. Hayes, Inc