Treatment options for male erectile dysfunction: a systematic review of published studies of effectiveness part 1 and part 2

Adams E J, Flynn K L, Alligood E C
Record ID 32000008228
Authors' objectives:

To respond to a request to VA's Technology Recommendations Panel (TRP) regarding treatment options for organic erectile dysfunction (ED).

Authors' results and conclusions: Relative comparisons of costs, contraindications, side effects and patient acceptability profiles are difficult since randomized controlled trials directly comparing the available treatments do not exist. Inconsistent or lack of clinically relevant reported outcomes, insufficient long-term follow-up and selection bias of enrolled patients further limit generalization from existing research. The number of male veterans with ED and their associated treatment outcomes and patient/partner preferences are unknown but are likely significant to the VA healthcare system.
Authors' recommendations: VA produced a guideline on the management of ED, which generally concurs with the results of this review. The guideline does not recommend the use of yohimbine and reflects concerns that the literature on Viagra may not be generalizable to VAs population. The guideline and this review agree that randomized trials are needed to compare treatment options for ED in veterans or comparable populations. Formal cost-effectiveness analyses should incorporate the trial results to help guide efficient allocation of VA healthcare.
Authors' methods: Systematic review
Project Status: Completed
Year Published: 1999
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: United States
Organisation Name: VA Technology Assessment Program
Contact Address: Liz Adams, VA Technology Assessment Program, Office of Patient Care Services (11T), VA Boston Healthcare System Room 4D-142, 150 South Huntington Avenue, Boston, MA 02130 USA Tel: +1 617 278 4469; Fax: +1 617 264 6587;
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Copyright: U. S. Department of Veterans Affairs
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.