Genetic testing for Long QT syndrome to identify individuals at high-risk of sudden cardiac death
Mundy L, Hiller JE
Record ID 32012000209
English
Authors' recommendations:
Studies assessed in this summary indicate that genetic screening is a potentially useful tool in diagnosing asymptomatic patients who may be carriers of an undetected genetic defect. These defects may only become apparent at first clinical presentation, which may in some cases be a cardiac event that results in death. A single cost-effectiveness study indicated that screening probands was cost-effective, however this study was not extended to include screening for family members. The number of potential individuals who would require genetic screening for long QT syndrome would be small if screening was limited to only family members of probands and as such would not incur a great financial burden on the health system. However the benefit of identifying an undetected mutation to these individuals would be far reaching.
Details
Project Status:
Completed
Year Published:
2006
URL for published report:
Not Available
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
Australia
MeSH Terms
- Humans
- Genetic Testing
- Long QT Syndrome
- Death, Sudden, Cardiac
Contact
Organisation Name:
Adelaide Health Technology Assessment
Contact Address:
School of Public Health, Mail Drop 545, University of Adelaide, Adelaide SA 5005, AUSTRALIA, Tel: +61 8 8313 4617
Contact Name:
ahta@adelaide.edu.au
Contact Email:
ahta@adelaide.edu.au
Copyright:
Adelaide Health Technology Assessment (AHTA)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.