[Effect of atrial natriuretic peptide, ANP, on the need for dialysis, when used as treatment or prevention of acute renal failure in intensive care]

The Regional Health Technology Assessment Centre (HTA-centrum)
Record ID 32011001699
Swedish
Authors' objectives:

Can treatment and prevention of acute renal failure with ANP reduce the need for dialysis in intensive care patients?

Authors' recomendations: Acute renal failure following major surgery, including organ transplantation, often requires expensive dialysis care. Treatment and prevention with the use of ANP may reduce the need for dialysis by half in specific patient populations. The largest effect has been observed in patients with acute renal failure after major cardio-vascular surgery where the need for dialysis decreased to one third.The effect of ANP is clearly present in low dose treatment, but missing at high dose. Complications, mainly hypotension, are few and related to the dose. Future studies are particularly needed in patients following organ transplantation.
Details
Project Status: Completed
Year Published: 2009
English language abstract: An English language summary is available
Publication Type: Not Assigned
MeSH Terms
  • Atrial Natriuretic Factor
  • Critical Care
Contact
Organisation Name: The Regional Health Technology Assessment Centre
Contact Address: The Regional Health Technology Assessment Centre, Region Vastra Gotaland, HTA-centrum, Roda Straket 8, Sahlgrenska Universitetssjukhuset, 413 45 GOTHENBORG, Sweden
Contact Name: hta-centrum@vgregion.se
Contact Email: hta-centrum@vgregion.se
Copyright: The Regional Health Technology Assessment Centre (HTA-centrum), Region Vastra Gotaland
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