Second-line therapy for patients with diabetes inadequately controlled on metformin: a systematic review and cost-effectiveness analysis

Canadian Agency for Drugs and Technologies in Health
Record ID 32011001581
English
Authors' objectives:

1) To conduct a systematic review of the clinical evidence pertaining to second-line antidiabetes drugs for patients with type 2 diabetes inadequately controlled on metformin monotherapy.
2) To conduct a cost-effectiveness analysis of second-line antidiabetes drugs for patients with type 2 diabetes inadequately controlled on metformin monotherapy based on the results of the systematic review.

Authors' recommendations: Sulfonylureas are equally efficacious as other agents when used as second-line treatment after inadequate control with metformin monotherapy, and represent the most cost-effective treatment option.
Details
Project Status: Completed
Year Published: 2010
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Canada
MeSH Terms
  • Cost-Benefit Analysis
  • Hypoglycemic Agents
  • Metformin
  • Sulfonylurea Compounds
Contact
Organisation Name: Canadian Agency for Drugs and Technologies in Health
Contact Address: 600-865 Carling Avenue, Ottawa, ON K1S 5S8 Canada. Tel: +1 613 226 2553; Fax: +1 613 226 5392;
Contact Name: requests@cadth.ca
Contact Email: requests@cadth.ca
Copyright: Canadian Agency for Drugs and Technologies in Health (CADTH)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.