Office-based phototherapy for treatment of atopic dermatitis in adults
Atopic dermatitis (AD) is a common chronic skin disease with a prevalence of 2% to 10% in adults. The disease is characterized by itchiness, pruritus, and inflammation of the skin. Eczematous lesions are a hallmark of the disease, which have periods of exacerbations (flares) and/or remissions. The pathophysiology of AD involves the complex interaction between genetic and environmental factors, which lead to changes in immunoregulation and disruption of the skin barrier. The goal of conventional AD management is to reduce the frequency and severity of flares. Management of AD includes patient education, prevention through trigger avoidance and hydration, and treatment of flares through pharmacologic and nonpharmacologic therapies. Given that traditional first- and second-line therapies may not be effective and carry long-term side effects, artificial ultraviolet radiation has been investigated as a treatment adjunct or alternative to conventional treatments.
- Adult
- Phototherapy
- Workplace