[Clinical effectiveness and cost-effectiveness of central venous catheters treated with minocycline and rifampicin in preventing bloodstream infections in intensive care patients]
Neusser S, Bitzer EM, Mieth I, Krauth C
Record ID 32011001391
Authors' objectives: This evaluation addresses questions on medical effectiveness, cost-efficiency, and ethical, social, and legal implications of MR-CVC.
Authors' recommendations: The utilization of MR-CVC shows protective effects and contributes to cost savings. Nevertheless, the application of this technology can not be recommended without limitation. The large number of systematic reviews indicates uncertainties, especially regarding the risk for the development of resistance. One reason is that in-vitro studies did find indications for the emergence of resistant strains. To clarify the medical effectiveness, a larger RCT conducted without manufacturers support is essential. Questions concerning the risk of allergic reactions and the possible emergence of resistant strains should be clarified by surveillance.
Project Status: Completed
Year Published: 2012
URL for published report: http://portal.dimdi.de/de/hta/hta_berichte/hta329_bericht_de.pdf
English language abstract: An English language summary is available
Publication Type: Not Assigned
Organisation Name: German Agency for HTA at the German Institute for Medical Documentation and Information
Contact Address: German Agency for Health Technology Assessment at the German Institute for Medical Documentation and Information, Waisenhausgasse 36-38a, D-50676 Cologne Germany
Contact Name: firstname.lastname@example.org
Contact Email: email@example.com
Copyright: <p>German Agency for Health Technology Assessment at the German Institute for Medical Documentation and Information (DAHTA@ DIMDI)</p>
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.