Menopausal symptoms: comparative effectiveness review of therapies
Grant MD, Marbella A, Wang AT, Pines E, Hoag J, Bonnell C, Ziegler KM, Aronson N
Record ID 32011001372
English
Authors' objectives:
To systematically review and synthesize evidence evaluating the comparative effectiveness of treatments for menopausal symptoms, along with potential long-term benefits and harms of those treatments.
Authors' recommendations:
Women experiencing symptoms of menopause can consider a number of potential treatments of varying efficacy. From a large body of evidence, there is considerable certainty that estrogens are the most effective treatment for relieving vasomotor symptoms and are accompanied by the greatest improvement in quality-of-life measures. For other common symptoms—psychological, urogenital, and sleep disturbance—although estrogens are effective,some nonhormonal agents compare favorably. Estrogens are accompanied by potential long-term harms that require consideration. There is limited evidence on the potential consequences of long-term use of nonhormonal agents when those agents are used to treat menopausal symptoms.
Details
Project Status:
Completed
Year Published:
2015
URL for published report:
http://www.effectivehealthcare.ahrq.gov/ehc/products/353/2051/menopause-report-150305.pdf
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
United States
MeSH Terms
- Antidepressive Agents
- Complementary Therapies
- Estrogen Replacement Therapy
- Menopause
- Middle Aged
Contact
Organisation Name:
Agency for Healthcare Research and Quality
Contact Address:
The Evidence-based Practice Center (EPC) Program, Center for Evidence and Practice Improvement, 5600 Fishers Lane, Rockville, MD 20857, USA. Tel: +1 301 427 1550
Contact Name:
The EPC Program
Contact Email:
epc@ahrq.hhs.gov
Copyright:
<p>Agency for Healthcare Research and Quality (AHRQ)</p>
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.