[Low density lipoprotein apheresis as adjuvant treatment for familial hypercholesterolaemia]

Atienza Merino G
Record ID 32011001317
Authors' objectives:

To assess the effectiveness and safety of direct adsorption by haemoperfusion and immunoadsorption, as coadjuvant treatments for familial hypercholesterolaemia, and study their short-term effect on plasma lipoprotein levels and their long-term effect on the progress of cardiovascular disease.

Authors' recommendations: When it comes to reducing LDL cholesterol levels, the comparative effectiveness of both techniques appears to be similar, though more information is available on the DALI system. Reports show a high percentage of clinical improvement and a reduction in the appearance of critical cardiovascular episodes in the long term. These techniques would thus seem to be safe, with no evidence of adverse effects in 95% of sessions.
Project Status: Completed
Year Published: 2011
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Spain
MeSH Terms
  • Hypercholesterolemia
  • Lipoproteins, LDL
Organisation Name: Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS)
Contact Address: Conselleria de Sanidade, Xunta de Galicia, San Lazaro s/n 15781 Santiago de Compostela, Spain. Tel: 34 981 541831; Fax: 34 981 542854;
Contact Name: avalia-t@sergas.es
Contact Email: avalia-t@sergas.es
Copyright: Galician Agency for Health Technology Assessment (AVALIA-T)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.