Antibiotic infused bone cement for orthopedic surgeries: a review of the clinical benefit and harm
Murphy G, Spry C
Record ID 32011001316
English
Authors' recommendations:
There is some evidence from RCTs and cohort studies suggesting antibiotic-loaded bone cement reduces the rate of deep infection in patients undergoing primary hip or knee replacement surgery. No conclusions can be reached regarding the optimal dose or type of antibiotic in cement. Information on antibiotic related toxicity was not presented in either systematic review. No conclusions can be drawn regarding the efficacy or safety of antibiotic-loaded bone cement in patients with infected joint prosthesis.
Details
Project Status:
Completed
URL for project:
http://www.cadth.ca/media/pdf/htis/L0040%20Antibiotic%20Infused%20Bone%20Cement%20for%20Orthopedic%20Surgeries%20final.pdf
Year Published:
2008
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
Canada
MeSH Terms
- Anti-Bacterial Agents
- Orthopedic Procedures
Contact
Organisation Name:
Canadian Agency for Drugs and Technologies in Health
Contact Address:
600-865 Carling Avenue, Ottawa, ON K1S 5S8 Canada. Tel: +1 613 226 2553; Fax: +1 613 226 5392;
Contact Name:
requests@cadth.ca
Contact Email:
requests@cadth.ca
Copyright:
Canadian Agency for Drugs and Technologies in Health (CADTH)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.