Organic acid testing for autism: a review of the diagnostic accuracy
Polisena J, Agraez C
Record ID 32011001247
English
Authors' recommendations:
No relevant evidence was identified on the diagnostic accuracy of organic acid testing for autism. Two case studies were identified that reported the use of organic acid tests in children with autistic symptoms. Both studies reported levels of organic acids above the normal range for children with autistic symptoms, and one study found higher organic acid levels compared with those found in children without autistic symptoms. One study reported a reduction in the patient’s autistic-type symptoms and hyperactivity following a restricted diet in protein intake and treatment with sodium benzoate and arginine for one year.According to the current literature, the diagnostic accuracy of organic acid testing for autism cannot be determined. The limited available evidence should be considered when determining whether to the fund the practice of organic acid testing for autism.
Details
Project Status:
Completed
URL for project:
http://www.cadth.ca/media/pdf/L0122_Organic_Acid_Testing_final.pdf
Year Published:
2009
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
Canada
MeSH Terms
- Autistic Disorder
- Porphyrins
Contact
Organisation Name:
Canadian Agency for Drugs and Technologies in Health
Contact Address:
600-865 Carling Avenue, Ottawa, ON K1S 5S8 Canada. Tel: +1 613 226 2553; Fax: +1 613 226 5392;
Contact Name:
requests@cadth.ca
Contact Email:
requests@cadth.ca
Copyright:
Canadian Agency for Drugs and Technologies in Health (CADTH)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.