Urine based testing for gonorrhea and chlamydia: a review of diagnostic accuracy, cost-effectiveness, and compliance

Tran K, Nkansah E
Record ID 32011001244
Authors' recommendations: Overall, the identified literature reported that urine-based testing is either comparable or less sensitive than swab-based testing for detection of gonorrhea and chlamydia in men and women, depending on the types of test and types of specimen collection being compared.A self-obtained vaginal swab NAAT strategy in the detection of chlamydia was found least expensive and most cost-effective compared with urine or endocervical tests. For screening of gonorrhea in women, there was no clear evidence regarding cost-effectiveness comparing urine-based testing and swab-based testing. Self-taken specimen such as vaginal swab and urine in women was reported to be the preferred method over clinician-collected approach. For screening and diagnosis of gonorrhea and chlamydia, the identified guidelines have made recommendations regarding the types of test and types of specimen collection according to specific populations. No study regarding the stability of swab-based versus urine-based specimen during transportation or storage could be found.
Project Status: Completed
Year Published: 2009
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Canada
MeSH Terms
  • Chlamydia Infections
  • Mass Screening
  • Sexually Transmitted Diseases
  • Urinalysis
Organisation Name: Canadian Agency for Drugs and Technologies in Health
Contact Address: 600-865 Carling Avenue, Ottawa, ON K1S 5S8 Canada. Tel: +1 613 226 2553; Fax: +1 613 226 5392;
Contact Name: requests@cadth.ca
Contact Email: requests@cadth.ca
Copyright: Canadian Agency for Drugs and Technologies in Health (CADTH)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.