Descemet stripping automated endothelial keratoplasty: a review of the clinical and cost-effectiveness
Ho C, Cunningham J
Record ID 32011001227
English
Authors' recommendations:
The comparative evidence from the one prospective study identified suggested that DSAEK provides significantly better best-corrected visual acuity and higher improvement in refractory astigmatism than PK. DSAEK also seems to result in better uncorrected visual acuity compared with PK, but the difference was inconclusive. However, the study also showed that DSAEK had a significantly higher rate of graft dislocation as compared with PK. The health technology assessment found that DSAEK and DSEK were effective in the treatment of corneal endothelial disorders, although there was a 14% rate of graft dislocation. No economic analyses about DSAEK were identified. The limited information identified on the clinical and cost-effectiveness of DSAEK may be a consideration for decision-making. Randomized studies comparing DSAEK to other techniques as well as cost-effectiveness studies are needed.
Details
Project Status:
Completed
URL for project:
http://www.cadth.ca/media/pdf/L0143_Descemet_Stripping_final.pdf
Year Published:
2009
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
Canada
MeSH Terms
- Corneal Diseases
- Descemet Stripping Endothelial Keratoplasty
- Endothelium, Corneal
- Keratoplasty, Penetrating
Contact
Organisation Name:
Canadian Agency for Drugs and Technologies in Health
Contact Address:
600-865 Carling Avenue, Ottawa, ON K1S 5S8 Canada. Tel: +1 613 226 2553; Fax: +1 613 226 5392;
Contact Name:
requests@cadth.ca
Contact Email:
requests@cadth.ca
Copyright:
Canadian Agency for Drugs and Technologies in Health (CADTH)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.