Fecal immunochemical tests for colorectal cancer screening: a systematic review of accuracy and compliance

Mujoomdar M, Cimon K, Spry C
Record ID 32011001218
English
Authors' recommendations: The results of this review suggest that FIT may be effective as a method of screening for CRC and advanced adenomas, and that FIT may be more effective when compared to other screening tests, such as gFOBT. In particular, the HemeSelect, FlexSure OBT, and OC-Sensor Micro FITs have demonstrated improved diagnostic performance characteristics compared with the gFOBT. All included studies that compared participation rates of FIT with other screening tests demonstrated that FIT had higher completion rates than the other tests, including gFOBT. The type of FIT and associated costs, the appropriate hemoglobin cut-off to use, and the capacity for follow-up by colonoscopy or flexible sigmoidoscopy may contribute to deciding if FIT is an appropriate CRC screening tool.
Details
Project Status: Completed
Year Published: 2009
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Canada
MeSH Terms
  • Colorectal Neoplasms
  • Immunologic Tests
  • Mass Screening
  • Occult Blood
  • Predictive Value of Tests
Contact
Organisation Name: Canadian Agency for Drugs and Technologies in Health
Contact Address: 600-865 Carling Avenue, Ottawa, ON K1S 5S8 Canada. Tel: +1 613 226 2553; Fax: +1 613 226 5392;
Contact Name: requests@cadth.ca
Contact Email: requests@cadth.ca
Copyright: Canadian Agency for Drugs and Technologies in Health (CADTH)
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