Topical diclofenac for the treatment of musculoskeletal pain unrelated to osteoarthritis: a review of the clinical effectiveness

Tsakonas E, Argaez C
Record ID 32011001204
English
Authors' recommendations: The studies reviewed for this report suggest that in general, topical diclofenac (in gel and patch formulations), is safe and effective in reducing pain and improving physical function in non-OA musculoskeletal conditions over the short term. Two active control studies found the comparators to be more effective than topical diclofenac, although improvement in patients taking diclofenac was still observed. Another study found that effectiveness may differ between topical gel formulations of diclofenac. This then suggests that differences in Topical Diclofenac for Musculoskeletal Pain effectiveness may exist between gel, solution, and patch-delivered formulations of diclofenac as well. Based on the evidence found in this review, no conclusions can be drawn regarding the effectiveness of topical solution formulations of diclofenac in non-OA musculoskeletal indications.
Details
Project Status: Completed
Year Published: 2009
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Canada
MeSH Terms
  • Administration, Cutaneous
  • Anti-Inflammatory Agents, Non-Steroidal
  • Muscle, Skeletal
  • Pain
Contact
Organisation Name: Canadian Agency for Drugs and Technologies in Health
Contact Address: 600-865 Carling Avenue, Ottawa, ON K1S 5S8 Canada. Tel: +1 613 226 2553; Fax: +1 613 226 5392;
Contact Name: requests@cadth.ca
Contact Email: requests@cadth.ca
Copyright: Canadian Agency for Drugs and Technologies in Health (CADTH)
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