[Percutaneous acrylic vertebroplasty for the treatment of vertebral fractures]
Pichon Riviere A, Augustovski F, Garcia Marti S, Glujovsky D, Lopez A, Rey-Ares L, Bardach A, Regueiro A, Alcaraz A, Valanzasca P, Elorriaga N, Romano M, Rojas J
Record ID 32011000976
Spanish
Authors' objectives:
To assess the available evidence on the efficacy, safety and issues related to coverage policies on the use of percutaneous acrylic vertebroplasty to relieve symptoms in vertebral fractures resulting from osteoporosis or tumor metastasis.
Authors' recommendations:
Percutaneous acrylic vertebroplasty has been proposed as a therapeutic alternative to reduce pain and improve motility in patients with vertebral compression fractures and painful fractures mainly secondary to osteoporosis, metastatic fractures or multiple myeloma.It is an effective therapy and has a low rate of adverse effects. As regards the usefulness of PVP in osteoporotic vertebral fractures, the evidence recently found in two randomized, blind, controlled clinical trials with few patients show that PVP is not better than standard treatment. For these studies, it is worth mentioning that, in order to keep the double-blind status, a vertebral infiltration with local anesthetics was performed; this intervention might have resulted in a beneficial effect in the control group. Two other randomized, controlled but open-label clinical trials did not show benefits with PVP over the conventional treatment either. Therefore, considering what is herein stated, conventional treatment is still the first choice for osteoporotic vertebral fractures.As regards the usefulness of PVP in the treatment of fractures secondary to metastasis or multiple myeloma, no randomized, controlled clinical trials have been found. The evidence from case series suggests that PVP might be useful in these patients. It is necessary to conduct clinical trials with an adequate number of patients, with a representative control group and adequate methodological quality in order to assess PVP usefulness for these indications.
Details
Project Status:
Completed
URL for project:
http://www.iecs.org.ar/iecs-visor-publicacion.php?cod_publicacion=1214&origen_publicacion=publicaciones
Year Published:
2011
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
Argentina
MeSH Terms
- Humans
- Spinal Fractures
- Vertebroplasty
Contact
Organisation Name:
Institute for Clinical Effectiveness and Health Policy
Contact Address:
Dr. Emilio Ravignani 2024, Buenos Aires - Argentina, C1414 CABA
Contact Name:
info@iecs.org.ar
Contact Email:
info@iecs.org.ar
Copyright:
Institute for Clinical Effectiveness and Health Policy (IECS)
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