Chronomodulated chemotherapy for metastatic colorectal cancer
Record ID 32011000882
English
Authors' objectives:
Chronomodulated chemotherapy for colorectal cancer (CRC) is a procedure in which treatments are administered to the patient at specific times within the 24-hour day. In both host and cancer tissues, drug metabolism and susceptibility to drugs vary in a circadian (24-hour) manner. In particular, the efficacy of a cell cycle specific (CCS) cytotoxic agent is affected by the daily modulation of cell cycle activity in the target tissues. Chronomodulated chemotherapy aims at exploiting these biological rhythms to reduce toxicity and improve efficacy of the treatment.
Details
Project Status:
Completed
Year Published:
2010
URL for published report:
http://www.hayesinc.com/hayes/crd/?crd=11910
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
United States
MeSH Terms
- Antineoplastic Combined Chemotherapy Protocols
- Chemotherapy, Cancer, Regional Perfusion
- Neoplasm Metastasis
Contact
Organisation Name:
HAYES, Inc.
Contact Address:
157 S. Broad Street, Suite 200, Lansdale, PA 19446, USA. Tel: 215 855 0615; Fax: 215 855 5218
Contact Name:
saleinfo@hayesinc.com
Contact Email:
saleinfo@hayesinc.com
Copyright:
2010 Winifred S. Hayes, Inc
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.